Pathophysiology and Management of Hemostatic Alterations in Cirrhosis and Liver Transplantation

F. Arshad

Changes in the hemostatic system frequently occur in patients with advancing chronic liver disease, and as a consequence patients with chronic liver disease may suffer from both bleeding- and thrombotic complications. The aim of this thesis was to investigate and summarize the hemostatic function in patients with chronic liver disease prior to, during, and after orthotopic liver transplantation (OLT), and to provide insight into old and new hemostatic agents that might be helpful to decrease morbidity and mortality related to the hemostatic derangements in these patients.

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